25 may 2012, Massage can reduce the child's arms and hands and diapers clearly the painful needle sticks, two recent studies - May 2012 (Honolulu, Hawaii).
In one study, researchers massaging upper limbs of children in a neonatal intensive care unit (NICU) before administration of venipuncture for blood samples. In the second study, wrapped in blankets researchers from the children a heel stick. Both teams of researchers have investigated the pain of babies in the Neonatal Pain Profile (PIPP), a composite measure of heart rate, oxygen saturation, facial reactions to pain (grimacing, brow bulge, nasolabial folds and lips pursed), behavioral state and gestational age. The researchers reported the results of both studies at the American Pain Society (APS) annual scientific meeting .. 31 Babies with Doctors often adhere to the NICU babies with needles to test your blood or administer medication."In my clinical practice I have seen many children suffer," Yuen Mon Chik, MS, lead author of the massage parlor, told Medscape Medical News: "I wonder if there is a way to relieve pain." It can be difficult to give babies oral analgesics, Chik said a researcher at the U.S. Christian Hospital, Hong Kong, China. "In foreign hospitals, such as the use of sucrose. It is effective in some ways, but in some babies it is not appropriate for the immature gut." For the study of massage, Chik and his colleagues randomly 65 children with a gestational age 30 to 40 weeks divided into two groups. The 32 children in group 1 received a massage for 2 minutes before the first blood test. They have the usual treatment before his second venipuncture. In group 2, the order reversed - the usual care following massage. The researchers tracked babies behavior and physiological responses to an accountant in real time, right after the massage, and again in the first 30 seconds of sampling. A nurse who did not want the child a massage before venipuncture rated videos and biometric data of children and had met in PIPP. Scores of PIPP ranging from 0 to 21, wherein higher values indicate higher pain behaviors. The average pain score in the first group was 5.84 ± 3.51 and 12.66 ± 3.10 a massage without any massage. The respective values of the second group, 7.30 ± 4.43 and 11.33 ± 4.37. The researchers concluded that the technique effectively reduces the pain of babies. "After a massage, there appears to be no sorrow," says Chik. Kathleen Sluka, Ph.D., professor of physical therapy and rehabilitation science of pain at the University of Iowa in Iowa City, told Medscape Medical News that he was impressed that massage seems to reduce pain score as much as half. "This is a relatively large reduction in pain for something as simple as a 2-minute massage," says Sluka, who was not involved in the study. "It's very easy to do." She said that children who are prone to suffer from chronic pain, pain that develop in adulthood. "This can be very important from this perspective," he said. Wrap In the second study, so researchers at the Chinese University of Hong Kong, China, the impact of diapers for newborns. They included 27 randomized 27 preterm infants with and without intervention. They report that the average values were lower in the intervention group PIPP than in the control group during, immediately after and 2, 4 and 6 minutes after a heel stick (p = 0.001). The average heart rate and oxygen saturation was also lower in the intervention group than in the control group in all these points in time (p <.001). Both heart rate and oxygen saturation in infants in diapers back to baseline levels in 2 minutes, but lasted for 6 to 8 minutes for these guys back to baseline in the control group. The researchers do not show any side effects.Speculate that the proprioceptive sensory stimulation systems provide diapers, thermal and tactile pain can be achieved by control of the door to be reduced. Wrap perhaps less practical than massage because it is difficult to access veins of babies wrapped in blankets, Chik said. American Pain Society (APS) 31 th annual scientific meeting. Abstract # 333 and # 455th Presented at 16th May 2012. Ms. Chik, and Ms. Sluka has NOTHING relevant financial relationships.
INCIDENCE/PREVALENCE/BURDENS ASSOCIATED WITH CARDIOVASCULAR DISEASE (CVD)
The prevention of an initial and recurrent cardiovascular event and other complications, such as diabetes and kidney failure [also known as end-stage renal disease (ESRD) or chronic kidney disease (CKD) stage 5] is an important goal in patients with a history of CVD. Each year, approximately 185,000 Americans suffer a recurrent stroke, approximately 470,000 will have a recurrent coronary attack, and an estimated 325,000 will suffer a recurrent myocardial infarction. Secondary prevention strategies offer the opportunity to prevent further complications and improve outcomes by early detection and management of common comorbidities.
The burden on public health and the costs associated with chronic illnesses such as CVD, CKD, and diabetes remain high. An estimated 82.6 million American adults (1 in 3) have 1 or more types of CVD. Heart failure is the fastest-growing clinical cardiac disease entity in the Unit…
August 28, 2012 — Two next-generation mechanical clot retrievers — the Solitaire flow restoration device and the Trevo retriever — work better than the older Merci retriever in stroke patients who are not eligible for or do not respond to thrombolytic therapy, according to the results of 2 randomized comparison trials.
Both of the newer devices were significantly better at restoring blood flow in affected arteries when compared with the Merci device and had similar or better safety profiles, researchers say. These results, from the SWIFT andTREVO 2 trials, were published online August 26 in The Lancet.
"SWIFT and TREVO 2 are major steps forward in the successful treatment of acute ischemic stroke, and pave the way for new treatment options and further validation by additional trials," writes Philip B. Gorelick, MD, MPH, medical director of the Hauenstein Neuroscience Center in Grand Rapids, Michigan, in a linked Comment.
The US Food and Drug Administration (FDA) approved th…
Human epidermal growth factor receptor 2 (HER2) is overexpressed on the cell surface and/or there is gene amplification in approximately 20% of all breast cancers. As a result, approximately 45,000-46,000 American women develop HER2-positive breast cancer each year.[2,3] HER2 status has prognostic significance: HER2-positive tumors are more aggressive and, without specific therapy, are associated with worse outcomes. However, in 2012 the most important role of HER2 is determination of eligibility for HER2-targeted therapy with trastuzumab or lapatinib.[1,5]
Although HER2-targeted therapy has improved outcomes in early breast cancer and in the metastatic setting, in the latter case it is typical to see progression after an initial response.[6,7] Therefore, research continues into optimizing the use of currently available agents and into novel agents including the novel HER2 antibody pertuzumab, the conjugate trastuzumab emtansine, and novel tyrosine kinase inhibitor…