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U.S. Approves Health Exchanges in Four Republican-Governed States

WASHINGTON (Reuters) Jan 03 - U.S. officials on Thursday gave four states currently governed by Republicans the green light to set up their own health insurance exchanges under President Barack Obama's healthcare reform law, an initiative largely opposed by Republicans. The U.S. Department of Health and Human Services said Idaho, Nevada, New Mexico and Utah joined a list totaling 17 states and the District of Columbia that have all won conditional approval to establish their own state exchanges, with operations set to begin on January 1, 2014. A fifth Republican-governed state, Mississippi, applied to operate a state exchange, but has not received approval because of a dispute about how much authority state officials should exercise over the operations of its prospective online marketplace, officials said. The U.S. administration also cleared an exchange that Arkansas plans to run in partnership with the federal government. Delaware received approval for a similar partners...

Many Patients Unaware of Radiation Risk From CT Scans

By Genevra Pittman NEW YORK (Reuters Health) Jan 03 - One-third of people getting a CT scan didn't know the test exposed their body to radiation, in a new study from a single U.S. medical center. The majority of patients also underestimated the amount of radiation delivered by a CT scan, and just one in 20 believed the scan would increase their chance of ever getting cancer. The study's lead researcher, Janet Busey, said doctors need to do a better job of talking to patients about the risks and benefits of the tests, including about radiation exposure. One challenge is that there is still debate within the medical community about just how much long term cancer risk the scans carry, she said. That risk also depends on how many scans a patient gets and which organs are exposed to radiation. "There's no doubt, CT saves lives," Busey, from the University of Washington in Seattle, told Reuters Health. And their benefits usually outweigh their risks, she ad...

GI Bleeds: Withholding Transfusions Boosts Survival

Withholding transfusions until hemoglobin levels are lower than 7%, rather than 9%, improves overall survival by 45% in patients with acute upper gastrointestinal (GI) bleeding, according to a  study published  in the January 3 issue of the New England Journal of Medicine . "[This study] provides long-awaited evidence to guide practice and justify current recommendations for the management of upper gastrointestinal bleeding," asserts Loren Laine, MD, from the Yale University School of Medicine in New Haven and the VA Connecticut Healthcare System in West Haven, in an accompanying editorial . Although prior meta-analyses have largely excluded the potential for benefit with a liberal transfusion strategy, only 1% or less of included patients had acute GI bleeds, Dr. Laine writes. To examine the potential benefit of a more narrow approach, Càndid Villanueva, MD, from the Gastrointestinal Bleeding Unit, Department of Gastroenterology, Hospital de Sant Pau, Autonomous Uni...

No Increased Risk of Neurologic Complications With Transradial PCI

STOKE-ON-TRENT, United Kingdom  — Performing PCI via the radial artery does not increase the risk of neurological complications when compared with conventional transfemoral PCI, a new European analysis shows [1]. Researchers say the results are reassuring, given that more and more operators are beginning to switch over to the transradial approach for various procedures. "This analysis of almost 350 000 PCI procedures has not found any increase in the risk of neurologic complications associated with transradial access via either the right (the predominant radial artery used) or left radial artery," write Dr Karim Ratib  (University Hospital of North Staffordshire, Stoke-on-Trent, UK) and colleagues in their study, published online December 26, 2012 in the  American Heart Journal . "The results are reassuring, as the data were collected over a transitional period in UK access-site practice, during which transradial access increased from 17.1% to 50.8% of all PCI c...

Semantic Decision-Making Corrupted in MCI, AD

Patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) are consistently slower and less accurate than healthy control persons in making semantic decisions in response to stimuli with words and images, new research shows. Brady Kirchberg and colleagues at Hofstra North Shore–Long Island Jewish School of Medicine, Manhasset, New York, found that both MCI and AD groups were not only less accurate and slower than healthy control participants in making semantic decisions in response to word stimuli but also that the deficit worsened as the sizes of the objects being compared became more similar. When line drawings were used as stimuli, the size of the drawings themselves had an undue influence upon semantic knowledge judgments in the 2 groups, investigators add. Performance on the semantic distance task was also a "strong and significant" predictor of everyday functional capacity. Dr. Terry Goldberg "When MCI/AD patients have to ...

Dexpramipexole Fails in ALS

Biogen Idec reports that topline results of a phase 3 trial investigating dexpramipexole in patients with amyotrophic lateral sclerosis (ALS) failed to show a benefit on primary or secondary outcomes. The trial, called EMPOWER and including 943 patients with ALS, failed to meet the primary outcome, a joint rank analysis of function and survival called the Combined Assessment of Function and Survival. Other endpoints, including functional decline, survival, or respiratory decline, and subgroup analyses also failed to show efficacy with treatment, overall or for any subpopulation. "Based on these results, Biogen Idec will discontinue development of dexpramipexole in ALS," a statement from the company said. "We share the disappointment of members of the ALS community, who had hoped that dexpramipexole would offer a meaningful treatment option," Douglas E. Williams, PhD, executive vice president of research and development at Biogen Idec, said in the company st...

Unnecessary Pap Tests in Millions of US Women

In their  report  on cervical cancer screening released yesterday, the Centers for Disease Control and Prevention (CDC) startlingly estimated that 22 million women in the United States may have undergone such screening unnecessarily, because they had already had hysterectomies. An expert approached by  Medscape Medical News  to comment on the issue cautioned that the data collected by the CDC were from women self-reporting and so may be subject to bias. She also suggested that some of the unnecessary testing, which is contrary to guidelines that have been in place for a decade, may be due to confusion stirred up by educational campaigns for the human papilloma virus vaccine Gardasil (Merck & Co). The CDC analyzed data collected from 2000-2010 by the Behavioral Risk Factor Surveillance System on screening for cervical cancer using the Papanicolaou (Pap) test. In one of the articles published in  Morbidity and Mortality Weekly Report , the CDC highlig...